abstract：OBJECTIVES:There is little information about the impact of hyperglycaemia in twin pregnancies. The objective of our study was to evaluate the maternal, foetal and neonatal complications in patients with twin pregnancy and glucose intolerance defined by gestational diabetes mellitus and gestational mild hyperglycaemia. ...

journal_title：Diabetes & metabolism

authors： Poulain C,Duhamel A,Garabedian C,Cazaubiel M,Rejou MC,Vambergue A,Deruelle P

更新日期：2015-11-01 00:00:00

abstract：AIM:As the treatment of hyperglycaemia during pregnancy with diet or insulin reduces the risk of adverse maternal outcomes and perinatal complications, screening for gestational diabetes mellitus (GDM) is included, albeit to variable extents, in all guidelines of care for pregnant women. The aim of the present investig...

journal_title：Diabetes & metabolism

authors： Nicotra F,Molinari C,Dozio N,Castiglioni MT,Ibrahim B,Zambon A,Corrao G,Scavini M

更新日期：2015-09-01 00:00:00

abstract：AIM:This study evaluated the proportions of prandial (PHG) vs fasting hyperglycaemia (FHG) over 24h in a group of patients with type 2 diabetes (overall and for Caucasian vs Asian patients), and tested the hypothesis that an insulin regimen with a prandial component allows a greater response than basal insulin at low g...

journal_title：Diabetes & metabolism

authors： Scheen AJ,Schmitt H,Jiang HH,Ivanyi T

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVES:This study aimed to estimate, in a large group of Algerian adolescents, the prevalence of the metabolic syndrome (MetS), using four definitions (by Cook, De Ferranti, Viner and the IDF), and to test the validity of unique thresholds of waist circumference, waist/height ratio and BMI in screening for the MetS...

journal_title：Diabetes & metabolism

authors： Benmohammed K,Valensi P,Benlatreche M,Nguyen MT,Benmohammed F,Pariès J,Khensal S,Benlatreche C,Lezzar A

更新日期：2015-04-01 00:00:00

abstract：AIM:The purpose of this prospective study was to investigate the effect of alcohol consumption on the 10-year diabetes incidence. METHODS:In 2001-2002, a random sample of 1514 men (18-89 years old) and 1528 women (18-87 years old) was selected to participate in the ATTICA study (Athens metropolitan area, Greece). Amon...

journal_title：Diabetes & metabolism

authors： Koloverou E,Panagiotakos DB,Pitsavos C,Chrysohoou C,Georgousopoulou EN,Metaxa V,Stefanadis C,ATTICA Study group.

更新日期：2015-04-01 00:00:00

abstract：AIM:Our study explored the association between subtypes of increased fat mass (with or without associated metabolic alterations) and the presence of chronic kidney disease (CKD). METHODS:In this cross-sectional survey in China, body mass index (BMI) was used to assess fat mass. Metabolically healthy was defined as no ...

journal_title：Diabetes & metabolism

authors： Chen S,Zhou S,Wu B,Zhao Y,Liu X,Liang Y,Shao X,Holthöfer H,Zou H

更新日期：2014-12-01 00:00:00

abstract：:Sodium-glucose cotransporter type 2 (SGLT-2) inhibitors (canagliflozin, dapagliflozin, empagliflozin) are new glucose-lowering agents that exert their therapeutic activity independently of insulin by facilitating glucose excretion through the kidneys. However, this simple renal mechanism that results in sustained gluc...

journal_title：Diabetes & metabolism

authors： Scheen AJ,Paquot N

更新日期：2014-12-01 00:00:00

abstract：AIM:Adiponectin levels in skeletal muscle and adipose tissue have been reported to be involved in insulin resistance in rats fed with a high-fat diet (HFD). Our objective was to explore whether adiponectin is also expressed in the pancreas and what its potential role is during the development of type 2 diabetes (T2D) i...

journal_title：Diabetes & metabolism

authors： Liu XX,Liu KY,Li P,Han S,Peng XD,Shen L

更新日期：2014-11-01 00:00:00

abstract：:Type 2 diabetes mellitus (T2DM) is strongly associated with cardiovascular complications, especially coronary artery disease. Numerous epidemiological studies have shown a close relationship between major cardiovascular events and glycaemia, and several pathophysiological mechanisms have been described that explain ho...

journal_title：Diabetes & metabolism

authors： Scheen AJ,Charbonnel B

更新日期：2014-06-01 00:00:00

abstract：AIM:Experimental evidence suggests that osteocalcin is a key messenger that affects both adipocytes and insulin-producing β cells. Epidemiological cross-sectional studies have shown a negative association between plasma levels of osteocalcin and glucose. For this reason, the hypothesis that lower baseline osteocalcin p...

journal_title：Diabetes & metabolism

authors： Liatis S,Sfikakis PP,Tsiakou A,Stathi C,Terpos E,Katsilambros N,Makrilakis K

更新日期：2014-06-01 00:00:00

abstract：AIM:This report highlights the metabolic, endocrine and cardiovascular comorbidities in a case of familial partial lipodystrophy (FPLD), and also evaluates the efficacy and safety of metformin therapy. METHODS:Mutational analysis was carried out of the LMNA gene in a teenage girl with an FPLD phenotype. Insulin resist...

journal_title：Diabetes & metabolism

authors： Chirico V,Ferraù V,Loddo I,Briuglia S,Amorini M,Salpietro V,Lacquaniti A,Salpietro C,Arrigo T

更新日期：2014-06-01 00:00:00

abstract：:One major discovery of the last decade in the field of metabolic diseases is that the microorganisms comprising the gut microbiota are now considered a metabolic "organ", modulating multiple functions of the host, such as intestinal immune system maturation, adiposity, cardiac metabolism, liver triglyceride storage, a...

journal_title：Diabetes & metabolism

authors： Serino M,Blasco-Baque V,Nicolas S,Burcelin R

更新日期：2014-06-01 00:00:00

abstract：INTRODUCTION:Although it is important to screen women who have had gestational diabetes mellitus (GDM) for abnormal post-partum glucose levels, such testing is rarely performed. The aim of this study was to use data from the first observational phase of the IMPACT study to determine rates of screening within 6 months o...

journal_title：Diabetes & metabolism

authors： Bihan H,Cosson E,Khiter C,Vittaz L,Faghfouri F,Leboeuf D,Carbillon L,Dauphin H,Reach G,Valensi P

更新日期：2014-04-01 00:00:00

abstract：:Type 1 diabetes (T1D) is due to the loss of both beta-cell insulin secretion and glucose sensing, leading to glucose variability and a lack of predictability, a daily issue for patients. Guidelines for the treatment of T1D have become stricter as results from the Diabetes Control and Complications Trial (DCCT) demonst...

journal_title：Diabetes & metabolism

authors： Vantyghem MC,Defrance F,Quintin D,Leroy C,Raverdi V,Prévost G,Caiazzo R,Kerr-Conte J,Glowacki F,Hazzan M,Noel C,Pattou F,Diamenord AS,Bresson R,Bourdelle-Hego MF,Cazaubiel M,Cordonnier M,Delefosse D,Dorey F,Fayard A

更新日期：2014-04-01 00:00:00

abstract：AIM:This study compared the clinical and biochemical characteristics and microvascular complications found in three groups of type 2 diabetes (T2D) patients: Africans living in Africa; African immigrants living in France; and Caucasians living in France. METHODS:Diagnosed T2D Africans living in Cameroon (n=100) were c...

journal_title：Diabetes & metabolism

authors： Choukem SP,Fabreguettes C,Akwo E,Porcher R,Nguewa JL,Bouche C,Kaze FF,Kengne AP,Vexiau P,Mbanya JC,Sobngwi E,Gautier JF

更新日期：2014-02-01 00:00:00

abstract：AIMS:Recent evidence suggests an association between persistent organic pollutants (POPs) and type 2 diabetes. In two First Nations communities where wild food is consumed by a large portion of the population, we compared pollutants in plasma between diabetic and non-diabetic individuals, and investigated the strength ...

journal_title：Diabetes & metabolism

authors： Pal S,Blais JM,Robidoux MA,Haman F,Krümmel E,Seabert TA,Imbeault P

更新日期：2013-12-01 00:00:00

abstract：AIM:Different treatment strategies have been used to manage adolescents with poorly controlled type 1 diabetes. We investigated whether a brief elective hospital admission improves haemoglobin A(1c) (HbA(1c)) over 12 months. METHODS:We studied a retrospective cohort of adolescents with poorly controlled type 1 diabete...

journal_title：Diabetes & metabolism

authors： Millette M,Mok E,Legault L

更新日期：2013-12-01 00:00:00

abstract：AIM:This study investigated the relationship between endothelial dysfunction (ED) and arterial stiffness (AS) in adults with type 1 diabetes and no clinical cardiovascular (CV) disease. METHODS:A total of 68 patients with type 1 diabetes and 68 age- and gender-matched healthy (non-diabetic) subjects were evaluated. ED...

journal_title：Diabetes & metabolism

authors： Llauradó G,Ceperuelo-Mallafré V,Vilardell C,Simó R,Albert L,Berlanga E,Vendrell J,González-Clemente JM

更新日期：2013-09-01 00:00:00

abstract：AIM:This study assessed the prevalence of undiagnosed diabetes and a high risk for diabetes using glycated haemoglobin (HbA(1c)) values in middle-aged patients undergoing cataract surgery. METHODS:The study comprised 137 consecutive patients, aged 40 to 65 years, with no known diabetes undergoing cataract surgery at a...

journal_title：Diabetes & metabolism

authors： Feldman-Billard S,Sedira N,Boelle PY,Poisson F,Héron E

更新日期：2013-05-01 00:00:00

abstract：AIM:Online continuous glucose monitoring (CGM) during physical exercise would be highly useful in patients with insulin-treated diabetes. For this reason, this study assessed whether such a goal could be reached with a subcutaneous 'needle-type' enzymatic sensor. METHODS:Ten patients (five women/five men), aged 51 ± 1...

journal_title：Diabetes & metabolism

authors： Radermecker RP,Fayolle C,Brun JF,Bringer J,Renard E

更新日期：2013-05-01 00:00:00

abstract：AIM:Cardiovascular autonomic neuropathy (CAN) is a common but often overlooked complication of diabetes. Sympathetic C-fibers innervating sweat glands can be impaired early on in patients with diabetes. In this study, SUDOSCAN, a new non-invasive device that assesses sudomotor function was compared to methods generally...

journal_title：Diabetes & metabolism

authors： Yajnik CS,Kantikar V,Pande A,Deslypere JP,Dupin J,Calvet JH,Bauduceau B

更新日期：2013-04-01 00:00:00

abstract：:Glucagon-like peptide (GLP)-1 action involves both endocrine and neural pathways to control peripheral tissues. In diabetes the impairment of either pathway may define different subsets of patients: some may be better treated with GLP-1 receptor agonists that are more likely to directly stimulate beta-cells and extrap...

journal_title：Diabetes & metabolism

authors： Burcelin R,Thorens B,European Club for the study of GLP-1 (EuCSGLP-1).

更新日期：2013-04-01 00:00:00

abstract：:Incretin therapies such as dipeptidyl peptidase-4 inhibitors (DPP-4Is) and GLP-1 receptor agonists (GLP-1RAs) have become well-established treatments for type 2 diabetes. Both drug classes reduce blood glucose through physiological pathways mediated by the GLP-1 receptor, resulting in glucose-dependent enhancement of ...

journal_title：Diabetes & metabolism

authors： Vora J,Bain SC,Damci T,Dzida G,Hollander P,Meneghini LF,Ross SA

更新日期：2013-02-01 00:00:00

abstract：AIMS:The innate immune-receptor nucleotide oligomerization domain (NOD) protein recognizes intracellular bacterial peptidoglycan. Activation of the innate immune system contributes to the development and progression of insulin resistance. The present study aimed to determine the presence of NOD1 and NOD2 in human adipo...

journal_title：Diabetes & metabolism

authors： Zhou YJ,Zhou H,Li Y,Song YL

更新日期：2012-12-01 00:00:00

abstract：AIM:To evaluate the correspondence between first-trimester fasting glycaemia and the results of the OGTT in diagnosing gestational diabetes (GDM). METHODS:The medical records of all consecutive women who had undergone a diagnostic OGTT, performed according to the IADPSG, during the past year were retrospectively revie...

journal_title：Diabetes & metabolism

authors： Corrado F,D'Anna R,Cannata ML,Interdonato ML,Pintaudi B,Di Benedetto A

更新日期：2012-11-01 00:00:00

abstract：AIM:To compare continuous glucose monitoring (CGM) profiles on vildagliptin versus sitagliptin in addition to metformin, in patients with inadequately controlled type 2 diabetes mellitus (HbA(1c) 6.5-8.0%). METHODS:A multicenter, prospective, randomised, open-label study with blinded endpoint analysis. CGM data acquir...

journal_title：Diabetes & metabolism

authors： Guerci B,Monnier L,Serusclat P,Petit C,Valensi P,Huet D,Raccah D,Colette C,Quéré S,Dejager S

更新日期：2012-10-01 00:00:00

abstract：:The peroxisome proliferator-activated receptor protein gamma (PPARγ), a nuclear receptor involved in adipocyte differentiation, energy homoeostasis and fat storage, can lead, in rare cases of coding mutations, to familial partial lipodystrophy type 3 (FPLD3) with severe insulin resistance. PPARγ is also highly express...

journal_title：Diabetes & metabolism

authors： Castell AL,Hiéronimus S,Lascols O,Fournier T,Fénichel P

更新日期：2012-10-01 00:00:00

abstract：:The management of type 2 diabetes continues to evolve as new data emerge. Although glycaemic control is still important, other risk factors--such as hypertension, dyslipidaemia and obesity--must also be addressed in order to reduce the long-term risks of cardiovascular complications and mortality. In this context, tar...

journal_title：Diabetes & metabolism

authors： Cariou B

更新日期：2012-10-01 00:00:00

abstract：AIM:The clinical guidelines reported by the French-Speaking Diabetes Society (Société francophone du diabète) include updated recommendations for preconceptual planning and care in the management of pregnancy in women with type 1 diabetes mellitus (T1DM). METHODS:The working group included diabetologists, as well as a...

journal_title：Diabetes & metabolism

authors： Bismuth E,Bouche C,Caliman C,Lepercq J,Lubin V,Rouge D,Timsit J,Vambergue A,French-Speaking Diabetes Society.

更新日期：2012-06-01 00:00:00

abstract：:The Diabetes and Cardiovascular Disease study group of the Société francophone du diabète (SFD, French Society of Diabetes) in collaboration with the Société française de cardiologie (SFC, French Society of Cardiology) have devised a consensus statement on the care of the hyperglycaemic/diabetic patient during and in ...

journal_title：Diabetes & metabolism

authors： Vergès B,Avignon A,Bonnet F,Catargi B,Cattan S,Cosson E,Ducrocq G,Elbaz M,Fredenrich A,Gourdy P,Henry P,Lairez O,Leguerrier AM,Monpère C,Moulin P,Vergès-Patois B,Roussel R,Steg G,Valensi P,Diabetes and Cardiovascula

更新日期：2012-04-01 00:00:00

abstract：AIMS:To describe insulin therapy in patients with diabetes, to determine treatment costs and to compare costs among treatment regimens. METHODS:This observational study was performed by 734 French pharmacists. Adult patients filling an insulin prescription were invited to participate. Participants provided information...

journal_title：Diabetes & metabolism

authors： Charbonnel B,Penfornis A,Varroud-Vial M,Kusnik-Joinville O,Detournay B

更新日期：2012-04-01 00:00:00

abstract：AIMS:To evaluate the current procedures in French general practice of intensifying hypoglycaemic treatment in orally treated type 2 diabetic patients, according to the French recommendations. METHODS:Type 2 diabetic patient characteristics, HbA(1c) values, hypoglycaemic treatment and physician characteristics were col...

journal_title：Diabetes & metabolism

authors： Balkau B,Bouée S,Avignon A,Vergès B,Chartier I,Amelineau E,Halimi S

更新日期：2012-03-01 00:00:00

abstract：AIMS:This study aimed to describe the 1-year evolution of type 2 diabetes (T2D) patients who attended inpatients education, and to assess whether quarterly outpatients counseling visits by nurses and dietitians can improve metabolic control and health-related behaviours. METHODS:Following in-hospital educational sessi...

journal_title：Diabetes & metabolism

authors： Debussche X,Rollot O,Le Pommelet C,Fianu A,Le Moullec N,Régnier C,Boyer MC,Cogne M,Bakiri F,Schwager JC,Favier F

更新日期：2012-02-01 00:00:00

abstract：AIM:Injections and fingersticks administered to patients with diabetes in health care settings present a risk of blood exposure to the injector as well as other workers in potential contact with sharps. Such exposures could lead to transmission of bloodborne pathogens such as hepatitis and HIV. A recent EU Directive re...

journal_title：Diabetes & metabolism

authors： Strauss K,WISE Consensus Group.

更新日期：2012-01-01 00:00:00

abstract：:Most primary-care physicians have adopted electronic medical records (EMRs) for the management of patients in ambulatory care. Observational trials suggest that the use of EMRs improves the achievement of the recommended standards of diabetes care and intermediate outcomes. A French group of general practitioners has ...

journal_title：Diabetes & metabolism

authors： Varroud-Vial M

更新日期：2011-12-01 00:00:00

abstract：AIM:This study aimed to assess whether group-based lifestyle counselling offered to a high-risk population subgroup had any effect beyond individual multifactorial interventions on fasting plasma glucose (FPG) and 2-h plasma glucose (2hPG) changes. METHODS:In a population-based study of 6784 participants, 4053 were de...

journal_title：Diabetes & metabolism

authors： Lau C,Vistisen D,Toft U,Tetens I,Glümer C,Pedersen O,Jørgensen T,Borch-Johnsen K

更新日期：2011-12-01 00:00:00

abstract：AIM:The prevalence of diabetes in the French West Indies is three times higher than in mainland France. We aimed to assess the associations between vitamin D deficiency, vitamin D receptor (VDR) gene polymorphisms and cardiovascular risk factors in Caribbean patients with type 2 diabetes (T2D). METHODS:In this cross-s...

journal_title：Diabetes & metabolism

authors： Vélayoudom-Céphise FL,Larifla L,Donnet JP,Maimaitiming S,Deloumeaux J,Blanchet A,Massart C,Munoz-Bellili N,Merle S,Chout R,Bonnet F,Foucan L

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Recently, the association of the natural variants rs1260326 and rs780094 of the glucokinase regulatory protein (GCKR) gene with increased fasting triglycerides and decreased fasting plasma glucose in diabetic adults was reported; the minor alleles were also found to reduce the risk of type 2 diabetes. The pre...

journal_title：Diabetes & metabolism

authors： Horvatovich K,Bokor S,Polgar N,Kisfali P,Hadarits F,Jaromi L,Csongei V,Repasy J,Molnar D,Melegh B

更新日期：2011-11-01 00:00:00

abstract：AIM:The best way to treat pregnant patients who have type 1 diabetes is still unclear. For this reason, the present study compared metabolic control and maternal-fetal outcomes in patients treated with continuous subcutaneous infusions of rapid-acting insulin analogues (CSII) or with insulin glargine and multiple daily...

journal_title：Diabetes & metabolism

authors： Bruttomesso D,Bonomo M,Costa S,Dal Pos M,Di Cianni G,Pellicano F,Vitacolonna E,Dodesini AR,Tonutti L,Lapolla A,Di Benedetto A,Torlone E,Italian Group for Continuous Subcutaneous Insulin Infusion in Pregnancy.

更新日期：2011-11-01 00:00:00

abstract：AIMS:To evaluate whether perception of insulin therapy differs between patients with type 2 diabetes treated with insulin and those treated with oral hypoglycaemic agents (OHAs), and to examine whether gender, education level, injection duration and mode of injection were associated with the patients' perception of ins...

journal_title：Diabetes & metabolism

authors： Chen CC,Chang MP,Hsieh MH,Huang CY,Liao LN,Li TC

更新日期：2011-11-01 00:00:00